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Vol.23, No.2

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Authors in this issue:

Zishan Wang, Chenwei Li, Xinjian Li, Jianguang Shi, Weijie Wu, Angela Pia Cazzolla, Roberto Lovero, Francesca Spirito, Michele Di Cosola, Luigi Santacroce, Eleonora Lo Muzio, Domenico Ciavarella, Mario Dioguardi, Vito Crincoli, Maria Pepe, Lucia Varraso, Renato Contino, Francesca Di Serio, Lorenzo Lo Muzio, Marek Bužga, Matej Pekař, Jaroslav Uchytil, Veronika Horká, Jan Malůš, Dominik Vilímek, Zdeněk Švagera, Petr Kutáč, Pavol Holéczy, Stasa Krasic, Sanja Ninic, Sergej Prijic, Sasa Popovic, Srdjan Pasic, Gordana Petrovic, Boris Zec, Snezana Ristic, Dejan Nesic, Luka Nikolic, Vladislav Vukomanovic, Dan Li, Xiaoxiao Liu, Yuchen Wang, Yingying Jin, Fang Li, Hongbing Ma, Kai Sun, Jun Wang, Wen-Min Chen, Nan Xu, Ling-Yu Long, Xu Wang, Hao Jiang, Qian Jiang, Xiao-Jun Huang, Ya-Zhen Qin, Jieqiu Zhang, Gaofei Cao, Haowen Pang, Jin Li, Xiaopeng Yao, Elina Beleva, Snezhana Stoencheva, Tanya Deneva, Ivanka Nenova, Zhanet Grudeva-Popova, Weiwei Li, Mohan Dong, Shigao Huang, Liu Shi, Hua Yang, Ying Zhang, Jie Gong, Mei Shi, Lichun Wei, Lina Zhao, Yanhui Chen, Yongrong Zhang, Cheng Rao, Jieyun Huang, Qiong Qing, Milica Živanović, Aleksandra Aracki Trenkić, Vuk Milošević, Dragan Stojanov, Miroslav Mišić, Milica Radovanović, Vukota Radovanović, Siqi Liu, Qian Zhang, Mengyao Zhang, Xuejing Zhong, Wudong Wang, Lishuang Wang, Zhenjing Jin, Run Zhang, Quan-Bing Zhang, Yun Zhou, Rui Zhang, Feng Wang, Saif Badran, Suhail A Doi, Moustapha Hamdi, Atalla Hammouda, Sara Alharami, Justin Clark, Omran A H Musa, Abdul-Badi Abou-Samra, Abdella M Habib, Ren Wang, Jie Lian, Xin Wang, Xiangyi Pang, Benjie Xu, Shuli Tang, Jiayue Shao, Haibo Lu, Chunyue Feng, Fei Liu, Semir Vranic,

Published: 29.01.2024.

Contents

16.03.2023. Review article
Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: The effect of programmed training on the muscle tissue and anthropometric functions—A randomized controlled trial (SarxOb study protocol)

Obesity is a serious metabolic disease that significantly increases cardiovascular risks and other health complications. Sarcopenia is an independent risk factor for morbidity and mortality in patients suffering from obesity that increases the health risks and is associated with cardiac, respiratory, and other diseases. Bariatric and metabolic sur...

By MAREK BUŽGA, MATEJ PEKAŘ, JAROSLAV UCHYTIL, VERONIKA HORKÁ, JAN MALŮŠ, DOMINIK VILÍMEK, ZDENĚK ŠVAGERA, PETR KUTÁČ, PAVOL HOLÉCZY

16.03.2023. Review article
Intrinsic resistance and efficacy of immunotherapy in microsatellite instability-high colorectal cancer: A systematic review and meta-analysis

Some patients with microsatellite instability-high colorectal cancer (MSI-H CRC) have shown a poor response to immunotherapy in clinical trials. We investigated the intrinsic resistance to and efficacy of immunotherapy in patients with MSI-H CRC. The PubMed and Web of Science databases were searched using keywords such as “colorectal cancer,...

By REN WANG, JIE LIAN, XIN WANG, XIANGYI PANG, BENJIE XU, SHULI TANG, JIAYUE SHAO, HAIBO LU

16.03.2023. Review article
The role of magnetic resonance imaging in the diagnosis and prognosis of dementia

Dementia is a syndrome characterized by multidomain acquired chronic cognitive impairment that has a profound impact on daily life. Neurogenerative diseases such as Alzheimer’s disease or nondegenerative diseases such as vascular dementia are considered to cause dementia. The need for further diagnostic improvement originates from the preval...

By MILICA ŽIVANOVIĆ, ALEKSANDRA ARACKI TRENKIĆ, VUK MILOŠEVIĆ, DRAGAN STOJANOV, MIROSLAV MIŠIĆ, MILICA RADOVANOVIĆ, VUKOTA RADOVANOVIĆ

16.03.2023. Review article
Artificial intelligence in renal pathology: Current status and future

Renal biopsy pathology is an essential gold standard for the diagnosis of most kidney diseases. With the increase in the incidence rate of kidney diseases, the lack of renal pathologists, and an imbalance in their distribution, there is an urgent need for a new renal pathological diagnosis model. Advances in artificial intelligence (AI) along with...

By CHUNYUE FENG, FEI LIU

16.03.2023. Review article
Metabolic aspects of surgical subcutaneous fat removal: An umbrella review and implications for future research

Although obesity is a preventable disease, maintaining a normal body weight can be very challenging and difficult, which has led to a significant increase in the demand for surgical subcutaneous fat removal (SSFR) to improve physical appearance. The need for SSFR is further exacerbated because of the global rise in the number of bariatric surgerie...

By SAIF BADRAN, SUHAIL A DOI, MOUSTAPHA HAMDI, ATALLA HAMMOUDA, SARA ALHARAMI, JUSTIN CLARK, OMRAN A H MUSA, ABDUL-BADI ABOU-SAMRA, ABDELLA M HABIB

16.03.2023. Scientific article
Reduced circulating interleukin 35 is associated with enhanced peripheral T cell function in primary biliary cholangitis

Interleukin 35 (IL-35) mediates immunosuppression of T cells in autoimmune diseases. T cells play an important role in primary biliary cholangitis (PBC) with incompletely elucidated pathogenesis. Thus, we aimed to investigate the role of IL-35 regulation on T cells in PBC patients. Fifty-one PBC patients and 28 controls were enrolled in this study...

By SIQI LIU, QIAN ZHANG, MENGYAO ZHANG, XUEJING ZHONG, WUDONG WANG, LISHUANG WANG, ZHENJING JIN

16.03.2023. Scientific article
Deletion of sphingosine kinase 2 attenuates cigarette smoke-mediated chronic obstructive pulmonary disease-like symptoms by reducing lung inflammation

Cigarette smoke (CS) is the leading cause of chronic obstructive pulmonary disease (COPD), which is characterized by chronic bronchial inflammation and emphysema. Growing evidence supports the hypothesis that dysfunctional cystic fibrosis transmembrane conductance regulator (CFTR) is critically involved in the pathogenesis of CS-mediated COPD. How...

By YANHUI CHEN, YONGRONG ZHANG, CHENG RAO, JIEYUN HUANG, QIONG QING

16.03.2023. Scientific article
Effect of vascular endothelial growth factor rs35569394 in esophageal cancer and response to chemotherapy

The objective of this study was to investigate the possible association between the single-nucleotide polymorphism, rs35569394, of the vascular endothelial growth factor (VEGF) gene and the risk of esophageal cancer (EC) in the Han Chinese population. A total of 290 EC subjects and 322 ethnically matched unrelated healthy controls free from the es...

By ZISHAN WANG, CHENWEI LI, XINJIAN LI, JIANGUANG SHI, WEIJIE WU

16.03.2023. Scientific article
Possible mechanism of static progressive stretching combined with extracorporeal shock wave therapy in reducing knee joint contracture in rats based on MAPK/ERK pathway

The study aimed to observe the therapeutic effect of static progressive stretching (SPS) combined with extracorporeal shock wave therapy (ESWT) on extension knee joint contracture in rats and the effect on the mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) pathway in the development of joint capsule fibrosis. T...

By RUN ZHANG, QUAN-BING ZHANG, YUN ZHOU, RUI ZHANG, FENG WANG

16.03.2023. Scientific article
Assessment of clinical utility and predictive potential of pre-chemotherapy soluble urokinase plasminogen activator receptor: Observational single center study

Alteration of urokinase plasminogen activator receptor (uPAR) in neoplasms is a pre-requisite for invasiveness and metastatic ability. In the present study, we aimed to evaluate the relationship of pre-chemotherapy soluble uPAR (suPAR) with the odds for metastasis, lack of disease control, and its predictive ability for progression-free survival (...

By ELINA BELEVA, SNEZHANA STOENCHEVA, TANYA DENEVA, IVANKA NENOVA, ZHANET GRUDEVA-POPOVA

16.03.2023. Scientific article
Clinical features and outcomes of fusion gene defined adult Ph-negative B-cell precursor acute lymphoblastic leukemia patients: A single institutional report

More clinical studies are needed to clarify the risk stratification by the integration of all fusion genes in adult B-cell precursor acute lymphoblastic leukemia (BCP-ALL). A total of 320 consecutive adult Ph-negative BCP-ALL patients who had been tested classical fusions (KMT2A rearrangement and TCF3-PBX1) at diagnosis were further retrospectivel...

By KAI SUN, JUN WANG, WEN-MIN CHEN, NAN XU, LING-YU LONG, XU WANG, HAO JIANG, QIAN JIANG, XIAO-JUN HUANG, YA-ZHEN QIN

16.03.2023. Scientific article
Efficacy and safety of PEG-rhG-CSF in preventing chemoradiotherapy-induced neutropenia in patients with locally advanced cervical cancer

The standard of care for locally advanced cervical cancer is concurrent chemoradiotherapy, which is associated with significant toxicity, especially hematologic toxicity. To evaluate the efficacy and safety of pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) in preventing neutropenia during radical chemoradiotherapy ...

By WEIWEI LI, MOHAN DONG, SHIGAO HUANG, LIU SHI, HUA YANG, YING ZHANG, JIE GONG, MEI SHI, LICHUN WEI, LINA ZHAO

16.03.2023. Scientific article
Development and validation of radiomics machine learning model based on contrast-enhanced computed tomography to predict axillary lymph node metastasis in breast cancer

Preoperative identification of axillary lymph node metastasis can play an important role in treatment selection strategy and prognosis evaluation. This study aimed to establish a clinical nomogram based on lymph node images to predict lymph node metastasis in breast cancer patients. A total of 193 patients with non-specific invasive breast cancer ...

By JIEQIU ZHANG, GAOFEI CAO, HAOWEN PANG, JIN LI, XIAOPENG YAO

16.03.2023. Scientific article
Intensity-modulated radiation therapy for elderly patients with esophageal cancer: Our experience

The aim of this study was to discuss the treatment mode of radical radiotherapy (RT) for elderly patients with esophageal cancer (EC). The clinical data of 136 elderly patients (≥60 years old) with EC who received radical intensity-modulated RT in The Second Affiliated Hospital of Xi’an Jiaotong University from January 2015 to December 20...

By DAN LI, XIAOXIAO LIU, YUCHEN WANG, YINGYING JIN, FANG LI, HONGBING MA

16.03.2023. Scientific article
Analysis of cardiac manifestation and treatment of multisystem inflammatory syndrome in children related to SARS-CoV-2

Cardiovascular (CV) manifestations are common (35%–100%) in the multisystem inflammatory syndrome in children. Our study aimed to analyze treatment impact and CV involvement in patients with multisystem inflammatory syndrome in children. The retrospective cohort included 81 patients treated between April 2020 and December 2021 (9.3 ± ...

By STASA KRASIC, SANJA NINIC, SERGEJ PRIJIC, SASA POPOVIC, SRDJAN PASIC, GORDANA PETROVIC, BORIS ZEC, SNEZANA RISTIC, DEJAN NESIC, LUKA NIKOLIC, VLADISLAV VUKOMANOVIC

16.03.2023. Scientific article
Evaluation of qualitative and quantitative taste alterations in COVID-19

A large percentage of coronavirus disease 2019 (COVID-19) patients have taste dysfunction. Interleukin 6 (IL-6) levels in mild and moderate COVID-19 patients with the type (quantitative or qualitative) of taste disorders were compared in this observational study. The 208 COVID-19 patients (118 men and 90 women) revealing only taste dysfunctions as...

By ANGELA PIA CAZZOLLA, ROBERTO LOVERO, FRANCESCA SPIRITO, MICHELE DI COSOLA, LUIGI SANTACROCE, ELEONORA LO MUZIO, DOMENICO CIAVARELLA, MARIO DIOGUARDI, VITO CRINCOLI, MARIA PEPE, LUCIA VARRASO, RENATO CONTINO, FRANCESCA DI SERIO, LORENZO LO MUZIO

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